A reconstruction of sexual modes throughout animal evolution

Non-Catalytic Roles of Presenilin Throughout Evolution

Research into Alzheimer's disease pathology and treatment has often focused on presenilin proteins. These proteins provide the key catalytic activity of the γ-secretase complex in the cleavage of amyloid-β precursor protein and resultant amyloid tangle deposition. Over the last 25 years, screening novel drugs to control this aberrant proteolytic activity has yet to identify effective treatments...

A study on the evolution of sexual receptivity and plasma estradiol-17beta levels throughout the lactation period, in rabbits

This study was designed to determine the evolution of plasma estradiol 1 7-ß(E,) levels and sexual receptivity(S.R.), from days 1 to 30 of the lactation period in rabbits. E2and S. R. were measured daily in 12 lactating doe rabbits of the California X New Zealand breed with 7-10 pups/litter. E, levels were determined by immunoassay (ELISA), and S.R. by means of the turgidity and color of the vu...

Conservation of expression regulation throughout the animal kingdom

Following the increase in available sequenced genomes, tissue-specific transcriptomes are being determined for a rapidly growing number of highly diverse species. Traditionally, only the transcriptomes of related species with equivalent tissues have been compared. Such an analysis is much more challenging over larger evolutionary distances when complementary tissues cannot readily be defined. H...

Facilities for complainants of sexual assault throughout the United Kingdom.

BACKGROUND A sexual assault referral centre (SARC) is a model of service established to address the forensic and therapeutic needs arising following sexual assault. As yet, only a minority of urban areas in England are served by one, the rest of the United Kingdom (UK) being served by police victim examination suites. OBJECTIVE To examine variations in service offered to complainants of sexua...

Sexual dimorphism in the Drosophila metabolome increases throughout development